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[gse144136] Single-nucleus RNA-seq in the post-mortem brain in major depressi...
Number of resources: 34 (34 raw, 0 normalizations, 0 DE files)We performed high-throughput snRNA-seq using the 10X Genomics Chromium platform on archived post-mortem dorsolateral prefrontal cortex (BA9) tissue in MDD subjects who died by... -
[gse128840] Neuronal deletion of Gtf2i, associated with Williams syndrome, ca...
Number of resources: 6 (6 raw, 0 normalizations, 0 DE files)Williams syndrome (WS), caused by a heterozygous microdeletion in 7q11.23, is a neurodevelopmental disorder characterized by hypersociability and neurocognitive abnormalities.... -
[gse42546] Whole transcriptome analysis of postmortem human hippocampus denta...
Number of resources: 79 (79 raw, 0 normalizations, 0 DE files)We investigated the transcriptome of dentate gyrus (DG) granule cells in postmortem hippocampus from 79 subjects with mental illness (schizophrenia, bipolar disorder, major... -
[gse113798] m6A/m-Seq of human B-lymphocyte cell lines from healthy controls ...
Number of resources: 25 (25 raw, 0 normalizations, 0 DE files)N6-Methyladenosine (m6A) and N6,2′-O-dimethyladenosine (m6Am) are abundant mRNA modifications that regulate transcript processing and translation. The role of both, here termed... -
[gse101521] Whole-transcriptome brain expression and exon-usage profiling in ...
Number of resources: 86 (86 raw, 0 normalizations, 0 DE files)Brain gene expression profiling studies of suicide and depression using oligonucleotide microarrays have often failed to distinguish these two phenotypes. Moreover, next... -
[gse102556] Sex-specific Transcriptional Signatures in Human Depression
Number of resources: 281 (281 raw, 0 normalizations, 0 DE files)Rational: Major depressive disorder (MDD) is a leading cause of disease burden worldwide. While the incidence, symptoms and treatment of MDD all point toward major sex...