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Expression data from peripheral blood lymphocytes of major depression, subsyndromal symptomatic depression, and healthy controls

gse32280

Description

Several studies have suggested that SSD is a transitory phenomena in the depression spectrum and is thus considered a subtype of depression. However, the pathophysioloy of depression remain largely obscure and studies on SSD are limited. The present study compared the expression profile and made the classification with the leukocytes by using whole-genome cRNA microarrays among drug-free first-episode subjects with SSD, MDD, and healthy controls.; We used microarrays to detail the global programme of gene expression to develop blood-based gene expression profiles models for classification of subsyndromal symptomatic depression and major depressive disorder

Overall Design

The present study compared the expression profile and made the classification with the leukocytes by using whole-genome cRNA microarrays among drug-free first-episode subjects with SSD, MDD, and matched controls (8 subjects in each group). Support vector machines (SVMs) were utilized for training and testing on candidate signature expression profiles from signature selection step.

Histogram

Data and Resources

Raw Files [37]

Additional Info

Field Value
Source https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32280
Type of Data

Expression profiling by array

Technology

Microarray

GSE Submission Date 21/09/2011
GSE Authors Zhenghui,,Yi; Zezhi Li
Dataset Last Updated November 29, 2019, 13:27 (UTC)
Dataset Created November 29, 2019, 13:01 (UTC)